Monday, February 17, 2014

Max Adrenal 2.0 Has Landed


This picture makes my adrenals squeal with glee
  ***UPDATE***:  I know this blog is completely bush-league, hard to read.  I have the below breakdown of what's in Max Adrenal 2.0 in an easy-to-read (as in, font.  You'll have to look up the big words yourself) PDF.  Shoot me an email to mike@dynamicnutritioon.ca if you want a copy.

So it's finally here...Max Adrenal 2.0.  Before I get into the dirty details on the what, I feel I need to explain the back story.  As many of you know, I deal with analysis, interpreting, and attempting to treat the repercussions of adrenal dysfunction secondary to athletic training.  Aside from diet/lifestyle/programming, part of this entails supplementation.  I've used MANY different adrenal formulas in the past, and in all honesty, I've never been totally happy with any one single formula.  The best to date has been Peak Bio's Max Energy, which is no longer available to the masses for multiple reasons I won't get into here.  So, over a year ago I started along a path with an end goal in mind, and it has finally come to fruition.
Just to be clear, this isn't an endeavor to make a boatload of money---being a little cog in the big wheel of supplement manufacturing, profit is almost an impossibility.  Without droning on, I took it upon myself to create a formula *I* was happy with.
Prior to releasing, I wanted to compile a comprehensive breakdown of each and every component in the formula---first and foremost, for client education.  I always ask "why", and I expect no less of my clients.  If we do not question, then we find no answers.  And, without further ado, the nuts n' bolts of the formula:
Max Adrenal 2.0 Component Breakdown
Vitamin A: required for the conversion of cholesterol to steroid hormones


Vitamin C: The highest concentrations of vitamin C reside in the eyes, brain and adrenal glands; stress, infection and intense exercise all increase the cellular demand for vitamin C, with studies showing how blood levels of ascorbic acid fall at an increased rate during these time

Thiamine (B1), Riboflavin (B2), Pyridoxine (B6), Pantothenic Acid (B5): All B vitamins are essential in the Kreb’s cycle for conversion of fat, carbs and protein to energy.  Specific to the adrenal cascade, pantothenic acid is required for the production of co-enzyme-A, which is essential for the creation of acetylcholine and pregnenolone.  Thiamine is used in the biosynthesis of the neurotransmitter acetylcholine and gamma-aminobutyric acid (GABA).  Riboflavin, key in the citric acid cycle, is also a cofactor in the utilization of B6 in the creation of neurotransmitters serotonin and norepinephrine.

Zinc: Zinc is an essential trace element required for the activity of over 300 enzymes and is involved in most major metabolic pathways.  Zinc participates not only in catalytic processes, but also in the structure and stability of some regulatory proteins, as is essential for immune support and testosterone production.  Training reduces levels through metabolic use and sweat loss.

Adrenal/Spleen Extract:  Clinical experience has long endorsed the use of glandular extracts to support the activity of the target gland. Glandulars provide peptides and nutrient cofactors which are found in the gland itself when it is healthy and fully functioning, and which are required for the gland to carry out its biological functions.  A highly active mineralocorticoid, aldosterone, 19-hydroxy-11-desoxycorticosterone and a sodium-retaining substance have all been isolated from beef adrenal extract.
Despite the widespread belief that such peptide cofactors would be destroyed by the digestive process, it’s now known the main route of absorption of amino acids is, in fact, by active transport in the form of peptides, rather than by totally breaking down proteins into individual amino acids. Evidence has also accumulated that many surprisingly large polypeptides and even proteins are directly absorbed by the gut. 


DL-Phenylalanine: DLPA is a depression fighting mixture that combines two forms of the amino acid, phenylalanine. The L-portion of phenylalanine, found in protein-rich foods, bolsters mood-elevating chemicals in the brain, specifically dopamine and nor-epinephrine, while the “D” form of phenylalanine is made synthetically in a laboratory.  The mechanism of DL-phenylalanine's supposed antidepressant activity may be accounted for by the precursor role of L-phenylalanine in the synthesis of the neurotransmitters norepinephrine and dopamine.


L-Tyrosine: One of the 22 amino acids used in the formation of neurotransmitters like dopamine and norepinephrine.  It is also involved in the formation of thyroid hormones like triiodothyronine (T3) and thyroxine (T4).  Supplementation has shown greater efficacy to reduce perception of stress while under stress.


Rhodiola Rosea: A potent adaptogen that has been the focus of much research. Rhodiola provides a buffer to stress-related mental and physical fatigue.  Rhodiola contains a glycoside known as salisdroside. This component helps combat anxiety and aging, and has been investigated for use in high-altitude sickness, as it modulates EPO gene expression. Rhodiola suppresses the production of cortisol and increases levels of stress-resistant proteins. Studies have found that it restores normal patterns of eating and sleeping after stress, & combats mental and physical fatigue by affecting RPE (perception to STRESS).  


L-Methionine:  Methionine belongs to a group of compounds called lipotropics which help the liver to process fat in the body. Once in the liver, methionine is converted into SAM(s-adenosyl methionine); SAMe is known to have a high degree of efficacy in treating various forms of depression.  Methionine also converts the stronger and carcinogenic estradiol (E2) into estriol (E3) which is the “good” estrogen as compared to estradiol; imbalance is common in various form of adrenal dysfunction.  Methionine supports methylation pathways, which facilitate the conversion of norepinephrine to epinephrine, essential in the adrenal cascade.


Octocasonol: The main component of policosanol, a lipophilic component derived from Cuban cane sugar.   While initial studies concentrated on it’s ability to affect cholesterol levels, it also has positive neurological effects specific to reaction time and Ach (acetylcholine) release.


Schisandra Chinensis:  A vine native to northern China and Eastern Russia, commonly known as Wu Wei Zi, or “Five flavor berry”.  Much of the research that ahs been done on Schisandra Chinesis was done in Russia decades ago, hence the popularity with Eastern European athletes.  Noted is the ability to both raise and lower cortisol in response to stressors.


Bacopa Monnieri:  Bacopa (aka Brahmi) is an Indian Ayurvedic herb noted for its use as a nootropic, or “mental focusing & memory enhancing” agent, and also acts protectively in neurodegeneration.  It appears to work through enhancing synaptic transmission, and also acts as an anti-oxidant, hence the protective effects.


Eleutherococcus senticosus:  Commonly known as Siberian Ginseng or in Chinese medicine Ci Wu Ju.  Although it is not related to true ginseng (Panax ginseng), the name Siberian ginseng became popular based on potential properties similar to Panax ginseng. This adaptogenic herb has both properties of increasing work capacity and immunity.  Increased work capacity is thought to be due to increased oxygen efficiency through FFA use. Immunomodulating polysaccharides or saponins isolated from Siberian ginseng stimulate macrophages, promoted antibody formation, activated complement, and increased T lymphocyte proliferation.
Magnolia Officinalis:  Another herb traditional used in Chinese medicine; the bark contains the polyphenolic compounds honokiol and magnolol, which have been found to have neuroprotective and anxiolytic activity, the latter of which is due to the effect on GABA receptors and the attenuation of cortisol-induced stress perception.
Rehmannia Glutinosia:  Also known as Yukmijihwang-tang or Chinese foxglove; it contains vitamins A, B, C, and D, as well as the active component catalpol.  Regarded as a tonic herb and used in TCM for centuries, current well-controlled human data is still lacking.  That said, it shows promise as a neuro-protecting agent as well as a nootropic.
Bupleurum Falcatum:  Commonly known as Chinese Thoroughwax, it has been traditionally used to treat disorders of inflammation. One of the active components are saikosaponins; their metabolites have been shown to induce corticosterone activity, hence it use as an adrenal tonic in TCM.  It also shows serotonergic and noradrenergic activity, and therefore used as an anti-depressant.
Panax Ginseng:  Also known as Red or Korean ginseng (not to be confused with Siberian). The predominant pharmacologically active constituents of Panax are ginsenosides; at least 25 of which have been identified and are present in variable amounts and ratios, depending on the particular species.  One of the most studies herbal adaptogens in history, its efficacy in treating fatigue, mood, immune system and adrenal issues is second to none.
Plectranthus Barbatus (Forskolii):  Better known as Coleus Forskoli, the active component tis forskolin, which stimulates the cellular production of cAMP.  When cAMP increases, a wide range of signaling properties can occur because of it.  While much research has been done on upregulation of cAMP and fat loss, recent research suggests that cAMP affects the function of higher-order thinking in the prefrontal cortex through its regulation of ion channels.  Much of the marketed focus has been on the ability to increase testosterone, which plays an integral role in the treatment of adrenal dysfunction.
Withania Somnifera:  Another Ayurvedic herb, Ashwagandha, aka Indian Ginseng, rivals that of Panax. Ginseng in the amount of positive data available.  It shows adaptogenic properties both in attenuating stress perception, altering cortisol, and increasing TTE (time to exhaustion) in trained athletes.  The potentially active constituents of ashwagandha include alkaloids and steroidal lactones that together are called withanolides (particularly withaferin A), and preparations are often standardized to their percentage contents of withanolides, as with the trademarked Sensoril brand.
And that's what in it.  Just a few select items.  Ha!  Now, the who, where, how do I buy all of Mike's limited stock, etc...
Who:  For those experiencing unexplained fatigue, decreased mental function, and inability to recover from regualr training.  Optimally, this would correspond w/ diagnostic lab values showing adrenal dysfunction.
Where: From me, obviously.  I have it listed on my website, but seriously, that thing is a static boat anchor, not sure if it even works.  Best way to contact me is via email, at mike@dynamicnutrition.ca
Cost: Intro price is at $35.00/container (30 day supply) + shipping.  
 Half-Assed End-Disclaimer
This product is not meant to treat serious disease processes.  It won't turn you into RF, Jr (you need PB & J for that).  It won't make you not suck if you suck already due to shitty lifestyle choices.  It won't make you smart if you are already dumber than a sack of shit.  It will most definately not fix fucking brutal dot-com group programming (get a coach!).  If your brain turns into moldy Paleo stew, it ain't my fault, bro, its that shitty mezcal you drink.  Don't take more than what's listed, it's not candy, dumbass.  If you are seriously fucked up, see a doc, talk to me, get some labs done.

Friday, January 17, 2014

Fuck It! Let's Make Meth! (Or, Some Supplement Reviews)

Welp, that pretty much sums up my generalized feeling lately towards everything.  Since it's 11:03PM, and I should either be sleeping, analyzing labs and food logs, or making meth, I'll NOT turn this into a "where-the-fuck-have-you-been" post, and get right the hell to work.

One thing I'd like to state is I'm absolutely blown to shit that anyone still reads this blog.  It started as a soapbox/ranting outlet, but I *STILL* get emails/texts etc asking me to update it.  Some shit in this world just plain amazes me.  Ok, enough!

AmateurVille Supplement Reviews

HAD to title it like that.  Had to.  Why?  Well, because one guy testing anything is a joke.  Paleo nerds have taken the n=1 and run around like a teenager with a hard on, thinking they are special, when in fact they look like idiots, and n=1 just means you are fucking around.

But apparently some folks think I'm test worthy, and I got some free shit in the mail.  Yay me.  In my next life, I swear to god I'm going to be something other than the "nutrition" guy, so I can get shit like free cars and blondes and drugs in the mail, instead of supplements and pictures of food.  Enough bitchin' though, onto the reason you are actually reading this blog!


Trial #1: Myothon


This was the first cold-call for me to test a supplement; I was initially caught off guard, thought it was bullshit spam, then re-read the email, and responded.  Myothon is made by a company called Vitality Sciences.  I hadn't heard of them before, looks like they are targeting both the endurance crowd and CF.  So what is Myothon all about?
  • It's basically a BCAA with 5 added EAAs.  If you need to look up those abbreviations, go look at pics of hot CF chicks on instagram, or something.
  • A single dose is 5 tabs, at roughly 2.5g BCAA, 2.5g of their EAA mix.
What I did:
  • I altered NOTHING in my preWO or PWO routine.  I normally take 15g BCAAs in addition to some other goodies.
  • I took 5 tabs Myothon in addition to my regular supplementation.
  • During this time I was training consistently at 11AM, sleep was good, diet is dialed (damn well better be), training Rx'd by Mike FitzGerald, geared for CF performance.
Effects:
  • Training sessions seemed more intense
  • Hit a lot of PR's strength wise in that cycle.
  • Recovery was good, not "I'm mainlining Winstrol" good, but good.
Impressions & Thoughts
  1. I was honestly surprised.  I expected fuck all.  Seriously, shit felt good all around during this testing phase.
  2. This was RIGHT before my 2nd daughter was born.  Sleep had not gone out the window, and stress was at a 2 year low.
  3. This formula is basically a rip off of the VERY overpriced MAP Master Amino Pattern.   
  4. I'm not 100% sure Mython, or anything like it, is worth it.  At 45 bucks for a bottle of 100 tabs, you'd rip through it trying to get 10g of BCAAs preWO (which is a legit ergogenic dose).
  5. That said, is it worth it to stack this with BCAAs?  Maybe.  BIG fucking maybe...
  6. Company makes a lot of claims with zero research.  
Would I Buy It:  Maybe.  I think there *IS* merit in using EAAs vs BCAAs, but the jury is still out, and most EAAs are too fucking pricey.

Trial #2: AMRAP Red Beet Powder preWO
This was exciting...not as exciting as getting free drugs in the mail, but pretty fucking close.  Taryn (totally off topic, but all 3 Taryn's I know exist in the CF community, and two are mentioned in this blog post.  Weird.  WEIRD) from AMRAP Nutrition contacted James FitzGerald at OPT, looking for some input on this new supplement.  James sent them to me, and I got the above in the mail.  VERY mysterious, all white and unlabeled and shit!  Wooo!  So, what was the deal with this new preWO from AMRAP?
  • It's based around the nitrates in beets.  Whats the scoop with that?  Oddly enough, I wrote a blog post for OPT at the exact time Taryn contacted me (seriously, I couldn't make this shit up.  I was in AZ at the time, too).  Read it HERE.
  • I received just TWO of the above packages.  Zero info on the dose or the nitrate concentration.
What I Did:
  • As above.  I took 1/2 the powder in water, to test the taste/palatability.  The other 1/2 I dumped into my BCAA drink.
  • I found the taste just fine.  Tasted like liquid beets.  If you don't like beets, you won't like it.  Someone else I know who is a certified baddass in the S & C world CC'd me on a email crying about the taste.  Seriously, it's beets.  C'mon.
Impression & Thoughts
  • 2 doses in a one man testing scenario amounts to, well...not much tested.
  • Expect to see a fuck ton of similar supplements in the near future.
  • Is there merit to this?  YES.  I absolutely think so, the science is legit and tight.  
  • I also think what will be IN a supplement and what WILL be needed for an ergogenic effect may be worlds apart, but that remains to be seen.  Nitrate amounts NEED to be listed on the label.  Most consumers are fucking retarded and buy supplements because its endorsed by some hot athlete.  But not all consumers are like that.  LIST THAT SHIT.
  • If you do nothing else, buy AMRAP bars.  They are clean and yummy.  And no, they didn't send me any.
Would I Buy It:  Maybe.  This supplement needs refining, but the science is definitely there.

Trial #3: HMB by Blonyx
Taryn from Blonyx was the 2nd of the 3 Taryns (the 3rd would be certified badass Taryn Romanowich).  Blonyx is a supplement company marketing two things to the CF community: HMB and creatine.  I have to admit up front I was hesitant to trial HMB, as the track record of efficacy in PERFORMANCE is just not there.  So, I admittedly went into this biased, but did my best to gauge the results as they were.

Without going into the whole history of HMB (Coles Notes:  Came into light in the 80's, research found it was pretty much useless except in untrained men playing video games in their parent's basement, then thrown into the gym and forced to consume HMB and do back squats, so it fell out of favor), recent research DOES show some promise (but there's a caveat, trust me), hence the re-emergence.

What I Did:
  • Same shit, different supplement.  As per the bottle, 2 capsules, 3x/day, for a total of 3g HMB.
  • Training, diet, awesome lifestyle unchanged.
Impression & Thoughts  
  • I hate to say this, and I SWEAR I'm not making it up, but I was MORE sore.  I seriously do NOT know how this could be, and I'm NOT blaming the supplement, by any means.  Looking back at my training cycle, it did not differ vastly from month before, perhaps more Oly work, perhaps more frequent squating, but nothing new.
  • The above is also boggling in that most of the positive research behind HMB involved a reduction in muscle damage and markers of such like LDH.
  • No noticeable increase in performance, no PRs.
  • This is a supplement I've seen many athletes take.  I've basically told them "if you aren't paying for it, double the dose, and it may help".  If you have to pay for it, save your pennies.
  • This has been echoed by associates of mine in the BB community...anecdotal evidence of decreased DOMS at HIGH dose (10-12g).  Keep in mind they do crazy shit that make CF athletes look like pussies.
Bottom Line:  HMB is a metabolite of leucine; if you are eating 1g/lb protein from whole foods, taking 7-15g BCAAs preWO (leucine is a BCAA, usually found in a 2:1:1 ratio w/ isoleucine and valine), taking 30g whey isolate PWO....do you think HMB will do ANYTHING?

Bottom Line #2:  Do you think ANY of the subjects in ANY study EVER done on HMB was consuming the above diet?

Would I Buy It: No.  There's many things I would spend money on, but this is definitely not one of them.  Grass fed beef, high end whey isolate, a solid BCAA give you all the damn leucine a guy could want.


Future Stuff
I actually have some planned posts, it's just a time issue these days.  Upcoming ramblin':
  • Part 3 of The Athlete Fix
  • Another MLM company targets the CF community, and my take on it.
  • More Supplement reviews.  Here's a sneak peak I'll leave you with:




Sunday, July 28, 2013

Peak Athletic Development, Examine.Com Supplement Guide, and Upcoming Events

Check these guys out!
Every once in a while you come across some writings and teaching that are so clear, so profound, and resonate deeply---not often, mind you.  In this day and age of wanna-bes and copy cats, something "unique and new" seems like an oxymoron.  Fortunately, this isn't the case for the guys at Peak Athletic Development.  Consisting of Evan Peikon and Mike Reynolds, right out of the gate, these guys were blazing a trail of highly informative and intelligent posts based around the Sport of Fitness.  I came across one of Mike's posts on Crossfit Quality Control, and quickly realized there was a wealth of educational writing in the others, as well.  I was surprised to find a link to my blog, and after contacting Evan, decided to do an interview

I urge you to check out every post these guys have written, as all are gems.   Check back here soon for an interview with Evan!

Probably the #1 question I get on ANY topic is "What do you think about [insert supplement/herb/pill/magic powder]???".  And, I understand why---the amount of knowledge needed, and amount of time to stay informed, is practically impossible to stay on top of.  Fortunately, guys like Sol Orwell and Kurtis Frank exist.  They've created a massive database supplement guide, which is cross-referenced with HUMAN studies.  There's a ton of pseudo-science out there, and half my time researching is spent figuring which is marketing, and which is legit.  These guys have DONE that.

  I don't endorse many products---but this is one I use daily.  AND they update the references daily.   $40.00 for a lifetime of updated supplement knowledge?  Seems like a no brainer to me.  GRAB IT HERE.  Seriously, this is an unheard of amount of knowledge to be had.

Coming up at the beginning of Sept I'll be presenting at Optimum Performance Training in Calgary at Mike FitzGerald's Outside The Box competition & learning seminar.  Coach Fitz has been brewing this for a while, and wanted to make it different than most "Let's destroy some athletes in the off-season" typical comps.  Expect true tests of fitness, and on my end, I'll be doing 4 - 20 minute presentations on nutrition + fueling.  Looking forward to it!
Sept 30-Oct 1st I'll be back in sunny Scottsdale at the NEW OPT International Center for Fitness teaching the CCP Level-1 Nutrition.  I'm going to hang around for a few days, maybe house-shop (I'll leave that to your imagination as to why...) and then present some specific athlete case studies regarding functional labwork on Oct 4 at the CCP coaches day for the OPTathlon.  

After that....baby due beginning of Nov, so I might not bee seen for a few months!